W59L (p.Trp59Leu) variant of G6PC2 (Glucose-6-phosphatase 2)
W59L (p.Trp59Leu) in G6PC2 (Glucose-6-phosphatase 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
W59L (p.Trp59Leu) variant details
- p.Trp59Leu
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.704
- REVEL 0.64
- CADD 27.50
- PolyPhen-2 0.75
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available