Y81H (p.Tyr81His) variant of FUS (RNA-binding protein FUS)
Y81H (p.Tyr81His) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
Y81H (p.Tyr81His) variant details
- p.Tyr81His
- gnomAD rs1458159264
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.42
- CADD 25.90
- PolyPhen-2 0.73
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available