Y6H (p.Tyr6His) variant of FUS (RNA-binding protein FUS)
Y6H (p.Tyr6His) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
Y6H (p.Tyr6His) variant details
- p.Tyr6His
- TOPMed rs967554455
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- REVEL 0.56
- CADD 29.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available