Y66C (p.Tyr66Cys) variant of FUS (RNA-binding protein FUS)
Y66C (p.Tyr66Cys) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
Y66C (p.Tyr66Cys) variant details
- p.Tyr66Cys
- gnomAD 16-31183864-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.69
- MetaLR 0.73
- MetaSVM 0.58
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available