Y58C (p.Tyr58Cys) variant of FUS (RNA-binding protein FUS)
Y58C (p.Tyr58Cys) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
Y58C (p.Tyr58Cys) variant details
- p.Tyr58Cys
- gnomAD 16-31182647-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- REVEL 0.53
- MetaLR 0.66
- MetaSVM 0.40
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available