Y33D (p.Tyr33Asp) variant of FUS (RNA-binding protein FUS)
Y33D (p.Tyr33Asp) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
Y33D (p.Tyr33Asp) variant details
- p.Tyr33Asp
- gnomAD 16-31182571-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.53
- MetaLR 0.71
- MetaSVM 0.52
- CADD 29.30
- PolyPhen-2 0.64
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available