Y25* (p.Tyr25Ter) variant of FUS (RNA-binding protein FUS)
Y25* (p.Tyr25Ter) in FUS (RNA-binding protein FUS) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
Y25* (p.Tyr25Ter) variant details
- p.Tyr25Ter
- gnomAD 16-31182549-T-G
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.345
- CADD 35.00
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available
- Literature evidence available