Y17S (p.Tyr17Ser) variant of FUS (RNA-binding protein FUS)
Y17S (p.Tyr17Ser) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
Y17S (p.Tyr17Ser) variant details
- p.Tyr17Ser
- ExAC rs746625098
- TOPMed rs746625098
- gnomAD rs746625098
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.61
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available