T7S (p.Thr7Ser) variant of FUS (RNA-binding protein FUS)
T7S (p.Thr7Ser) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T7S (p.Thr7Ser) variant details
- p.Thr7Ser
- TOPMed rs978032980
- gnomAD rs978032980
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.21
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available