T78I (p.Thr78Ile) variant of FUS (RNA-binding protein FUS)
T78I (p.Thr78Ile) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T78I (p.Thr78Ile) variant details
- p.Thr78Ile
- Ensembl rs2144107368
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.10
- CADD 13.20
- PolyPhen-2 0.03
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available