Q60E (p.Gln60Glu) variant of FUS (RNA-binding protein FUS)
Q60E (p.Gln60Glu) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
Q60E (p.Gln60Glu) variant details
- p.Gln60Glu
- gnomAD 16-31182652-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.46
- MetaLR 0.65
- MetaSVM 0.19
- CADD 23.60
- PolyPhen-2 0.93
- SIFT 0.91
- Population evidence available
- Structural context available
- Literature evidence available