Q35L (p.Gln35Leu) variant of FUS (RNA-binding protein FUS)
Q35L (p.Gln35Leu) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
Q35L (p.Gln35Leu) variant details
- p.Gln35Leu
- gnomAD 16-31182578-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- REVEL 0.48
- MetaLR 0.68
- MetaSVM 0.47
- CADD 27.10
- PolyPhen-2 0.64
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available