G74A (p.Gly74Ala) variant of FUS (RNA-binding protein FUS)
G74A (p.Gly74Ala) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G74A (p.Gly74Ala) variant details
- p.Gly74Ala
- gnomAD rs1260300816
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.22
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.80
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available