G65D (p.Gly65Asp) variant of FUS (RNA-binding protein FUS)
G65D (p.Gly65Asp) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
G65D (p.Gly65Asp) variant details
- p.Gly65Asp
- gnomAD rs2079218084
- Missense
- Variant Prioritization Score for Impact Estimate 0.648
- REVEL 0.63
- CADD 26.00
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available