G51D (p.Gly51Asp) variant of FUS (RNA-binding protein FUS)
G51D (p.Gly51Asp) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G51D (p.Gly51Asp) variant details
- p.Gly51Asp
- gnomAD rs1306780434
- Missense
- Variant Prioritization Score for Impact Estimate 0.703
- REVEL 0.65
- CADD 26.80
- PolyPhen-2 0.48
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available