G49G (p.Gly49Gly) variant of FUS (RNA-binding protein FUS)
G49G (p.Gly49Gly) in FUS (RNA-binding protein FUS) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
G49G (p.Gly49Gly) variant details
- p.Gly49Gly
- rs741810
- gnomAD 16-31182621-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.372
- CADD 18.80
- Population evidence available
- Structural context available
- Cited in: Genetic testing of FUS, HTRA2, and TENM4 genes in Chinese patients with essential tremor. (PMID 32196977)
- Cited in: Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American… (PMID 25741868)