G24D (p.Gly24Asp) variant of FUS (RNA-binding protein FUS)
G24D (p.Gly24Asp) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
G24D (p.Gly24Asp) variant details
- p.Gly24Asp
- gnomAD 16-31182545-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.67
- REVEL 0.57
- CADD 29.40
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available
- Literature evidence available