G22R (p.Gly22Arg) variant of FUS (RNA-binding protein FUS)
G22R (p.Gly22Arg) in FUS (RNA-binding protein FUS) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- gnomAD rs1260673954
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.45
- CADD 24.70
- PolyPhen-2 0.54
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available