W42C (p.Trp42Cys) variant of FTO (Q9C0B1)
W42C (p.Trp42Cys) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
W42C (p.Trp42Cys) variant details
- p.Trp42Cys
- ExAC rs768675500
- TOPMed rs768675500
- gnomAD rs768675500
- Missense
- Variant Prioritization Score for Impact Estimate 0.755
- REVEL 0.71
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available