T6I (p.Thr6Ile) variant of FTO (Q9C0B1)
T6I (p.Thr6Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T6I (p.Thr6Ile) variant details
- p.Thr6Ile
- 1000Genomes rs546144833
- ExAC rs546144833
- gnomAD rs546144833
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.21
- CADD 22.80
- PolyPhen-2 0.37
- SIFT 0.05
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available