T6A (p.Thr6Ala) variant of FTO (Q9C0B1)
T6A (p.Thr6Ala) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T6A (p.Thr6Ala) variant details
- p.Thr6Ala
- TOPMed rs913398301
- gnomAD rs913398301
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.29
- CADD 22.50
- PolyPhen-2 0.06
- SIFT 0.27
- Most common in the REMAINING population (allele frequency 0.0001)
- Structural context available