T4I (p.Thr4Ile) variant of FTO (Q9C0B1)
T4I (p.Thr4Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T4I (p.Thr4Ile) variant details
- p.Thr4Ile
- gnomAD rs1456216323
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.09
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)
- Structural context available