T32N (p.Thr32Asn) variant of FTO (Q9C0B1)
T32N (p.Thr32Asn) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
T32N (p.Thr32Asn) variant details
- p.Thr32Asn
- gnomAD 16-53810189-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.14
- MetaLR 0.27
- MetaSVM -0.45
- CADD 23.70
- PolyPhen-2 0.76
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available