T32I (p.Thr32Ile) variant of FTO (Q9C0B1)
T32I (p.Thr32Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
T32I (p.Thr32Ile) variant details
- p.Thr32Ile
- TOPMed rs1194621251
- gnomAD rs1194621251
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.32
- CADD 24.30
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available