T26P (p.Thr26Pro) variant of FTO (Q9C0B1)
T26P (p.Thr26Pro) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
T26P (p.Thr26Pro) variant details
- p.Thr26Pro
- gnomAD 16-53810170-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.19
- MetaLR 0.11
- MetaSVM -0.90
- CADD 21.60
- PolyPhen-2 0.34
- SIFT 0.15
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available