T26I (p.Thr26Ile) variant of FTO (Q9C0B1)
T26I (p.Thr26Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
T26I (p.Thr26Ile) variant details
- p.Thr26Ile
- ExAC rs756522457
- TOPMed rs756522457
- gnomAD rs756522457
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.22
- CADD 20.60
- PolyPhen-2 0.36
- SIFT 0.11
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available