S58Y (p.Ser58Tyr) variant of FTO (Q9C0B1)
S58Y (p.Ser58Tyr) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S58Y (p.Ser58Tyr) variant details
- p.Ser58Tyr
- Ensembl rs1567332084
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.33
- CADD 23.20
- PolyPhen-2 0.65
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available