R3G (p.Arg3Gly) variant of FTO (Q9C0B1)
R3G (p.Arg3Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
R3G (p.Arg3Gly) variant details
- p.Arg3Gly
- gnomAD 16-53704191-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.35
- CADD 27.80
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available