R18G (p.Arg18Gly) variant of FTO (Q9C0B1)
R18G (p.Arg18Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
R18G (p.Arg18Gly) variant details
- p.Arg18Gly
- gnomAD 16-53810146-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.34
- MetaLR 0.14
- MetaSVM -0.91
- CADD 24.20
- PolyPhen-2 0.07
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available