R10L (p.Arg10Leu) variant of FTO (Q9C0B1)
R10L (p.Arg10Leu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R10L (p.Arg10Leu) variant details
- p.Arg10Leu
- 1000Genomes rs575883122
- ExAC rs575883122
- TOPMed rs575883122
- gnomAD rs575883122
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.12
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available