R10G (p.Arg10Gly) variant of FTO (Q9C0B1)
R10G (p.Arg10Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R10G (p.Arg10Gly) variant details
- p.Arg10Gly
- gnomAD 16-53704212-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.17
- CADD 18.20
- PolyPhen-2 0.02
- SIFT 0.34
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available