Q41R (p.Gln41Arg) variant of FTO (Q9C0B1)
Q41R (p.Gln41Arg) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
Q41R (p.Gln41Arg) variant details
- p.Gln41Arg
- gnomAD 16-53810216-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.33
- MetaLR 0.29
- MetaSVM -0.52
- CADD 23.90
- PolyPhen-2 0.39
- SIFT 0.06
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available
- Literature evidence available