Q41K (p.Gln41Lys) variant of FTO (Q9C0B1)
Q41K (p.Gln41Lys) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
Q41K (p.Gln41Lys) variant details
- p.Gln41Lys
- gnomAD 16-53810215-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.21
- MetaLR 0.26
- MetaSVM -0.58
- CADD 21.30
- PolyPhen-2 0.30
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available