P5R (p.Pro5Arg) variant of FTO (Q9C0B1)
P5R (p.Pro5Arg) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P5R (p.Pro5Arg) variant details
- p.Pro5Arg
- TOPMed rs1035019229
- gnomAD rs1035019229
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.09
- CADD 11.50
- PolyPhen-2 0.03
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available