P5Q (p.Pro5Gln) variant of FTO (Q9C0B1)
P5Q (p.Pro5Gln) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P5Q (p.Pro5Gln) variant details
- p.Pro5Gln
- gnomAD 16-53704198-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.14
- CADD 9.41
- PolyPhen-2 0.00
- SIFT 0.83
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available