P5L (p.Pro5Leu) variant of FTO (Q9C0B1)
P5L (p.Pro5Leu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P5L (p.Pro5Leu) variant details
- p.Pro5Leu
- TOPMed rs1035019229
- gnomAD rs1035019229
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.17
- CADD 14.20
- PolyPhen-2 0.01
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 4.6e-05)
- Structural context available