P47S (p.Pro47Ser) variant of FTO (Q9C0B1)
P47S (p.Pro47Ser) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P47S (p.Pro47Ser) variant details
- p.Pro47Ser
- ExAC rs759800072
- gnomAD rs759800072
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.18
- CADD 18.30
- PolyPhen-2 0.03
- SIFT 0.92
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available