P47R (p.Pro47Arg) variant of FTO (Q9C0B1)
P47R (p.Pro47Arg) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
P47R (p.Pro47Arg) variant details
- p.Pro47Arg
- TOPMed rs1288155645
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.29
- CADD 24.10
- PolyPhen-2 0.77
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available