P33L (p.Pro33Leu) variant of FTO (Q9C0B1)
P33L (p.Pro33Leu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- gnomAD 16-53810192-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.52
- MetaLR 0.61
- MetaSVM 0.34
- CADD 24.90
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available