L23V (p.Leu23Val) variant of FTO (Q9C0B1)
L23V (p.Leu23Val) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L23V (p.Leu23Val) variant details
- p.Leu23Val
- TOPMed rs1211420864
- gnomAD rs1211420864
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.20
- CADD 18.60
- PolyPhen-2 0.21
- SIFT 0.10
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available