L23I (p.Leu23Ile) variant of FTO (Q9C0B1)
L23I (p.Leu23Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L23I (p.Leu23Ile) variant details
- p.Leu23Ile
- gnomAD 16-53810161-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.09
- MetaLR 0.14
- MetaSVM -0.84
- CADD 18.00
- PolyPhen-2 0.06
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available