L19I (p.Leu19Ile) variant of FTO (Q9C0B1)
L19I (p.Leu19Ile) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L19I (p.Leu19Ile) variant details
- p.Leu19Ile
- gnomAD 16-53810149-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.25
- MetaLR 0.45
- MetaSVM -0.03
- CADD 24.80
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available