K45E (p.Lys45Glu) variant of FTO (Q9C0B1)
K45E (p.Lys45Glu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
K45E (p.Lys45Glu) variant details
- p.Lys45Glu
- ExAC rs771274827
- gnomAD rs771274827
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.21
- CADD 23.00
- PolyPhen-2 0.32
- SIFT 0.07
- Population evidence available
- Structural context available