K2Q (p.Lys2Gln) variant of FTO (Q9C0B1)
K2Q (p.Lys2Gln) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K2Q (p.Lys2Gln) variant details
- p.Lys2Gln
- 1000Genomes rs201836578
- TOPMed rs201836578
- gnomAD rs201836578
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.27
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available