K2N (p.Lys2Asn) variant of FTO (Q9C0B1)
K2N (p.Lys2Asn) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K2N (p.Lys2Asn) variant details
- p.Lys2Asn
- gnomAD rs989161287
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- REVEL 0.26
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)
- Structural context available