K2E (p.Lys2Glu) variant of FTO (Q9C0B1)
K2E (p.Lys2Glu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
K2E (p.Lys2Glu) variant details
- p.Lys2Glu
- 1000Genomes rs201836578
- TOPMed rs201836578
- gnomAD rs201836578
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.30
- CADD 32.00
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available