K16Q (p.Lys16Gln) variant of FTO (Q9C0B1)
K16Q (p.Lys16Gln) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
K16Q (p.Lys16Gln) variant details
- p.Lys16Gln
- ExAC rs774232694
- TOPMed rs774232694
- gnomAD rs774232694
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.23
- CADD 28.40
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available