H62P (p.His62Pro) variant of FTO (Q9C0B1)
H62P (p.His62Pro) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
H62P (p.His62Pro) variant details
- p.His62Pro
- gnomAD 16-53825925-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.721
- REVEL 0.86
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available