F69L (p.Phe69Leu) variant of FTO (Q9C0B1)
F69L (p.Phe69Leu) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
F69L (p.Phe69Leu) variant details
- p.Phe69Leu
- gnomAD rs1352866890
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- REVEL 0.53
- CADD 24.00
- PolyPhen-2 0.99
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available