E8G (p.Glu8Gly) variant of FTO (Q9C0B1)
E8G (p.Glu8Gly) in FTO (Q9C0B1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
E8G (p.Glu8Gly) variant details
- p.Glu8Gly
- gnomAD rs1329981588
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.33
- CADD 24.50
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available